Migraine and nasal surgery for intranasal contact point, pathophysiology.
Understanding the role of contact points as an exacerbating factor for migraine requires a brief review of the anatomy of the nasal cavity. The nasal septum divides the nasal cavity into right and left chambers. The lateral walls of the nasal cavity consist of the superior turbinate, medial wall of the ethmoid sinuses, middle turbinate and inferior turbinate. Note the space between the septum and superior turbinate, medial walls of ethmoid sinuses and the middle turbinate.
If the septum is pressing against any structure of the lateral wall of the nasal cavity it creates a contact point which could be in one site or multiple sites. Contact point between the nasal septum and middle turbinate on the right side, and medial wall of ethmoid sinus on the left.
The Trigeminal nerve supplies sensation to the nasal cavity which also innervates the structures inside the skull.
The nasal mucosa and intranasal structures are very sensitive to pressure. When there is pain of certain intensity in the head and neck area (supplied by trigeminal nerve and cervical verves that are connected to each other) a special chemical (CGRP) secreted at the nerve ending which causes swelling of the nasal mucosa, This swelling will create more pressure on the septum at the contact point sites which translate to more pain therefore more CGRP secretion. This is a vicious cycle that gets worse as minutes go by. It takes about 20 to 30 minutes to build up (the usual time for the migraine headache from start to peak).
By removing the contact points in the nasal cavity the headaches will not progress to the maximum level and usually could be treated with mild pain killer or in the case of transformed migraine responds to migraine medications.